ویلم دفو در صحنه فیلم سینمایی Nymphomaniac: Vol. I به همراه Mia Goth، استیسی مارتین، Christian Slater، شارلوت گنزبور، لارس فون تریه، Shia LaBeouf، Sophie Kennedy Clark، جیمی بل، Udo Kier، کانی نیلسن، استلان اسکارشگورد، یوما تورمن و Nicolas Bro
A man named Seligman finds a fainted wounded woman in an alley and he brings her home. She tells him that her name is Joe and that she is nymphomaniac. Joe tells her life and sexual experiences with hundreds of men since she was a young teenager while Seligman tells about his hobbies, such as fly fishing, reading about Fibonacci numbers or listening to organ music.